EFFECTIVENESS OF PHARMACOTHERAPY OF HEMORRHAGIC CYSTITIS IN CATS
Keywords:
cats, hemorrhagic cystitis, hematuria, pharmacotherapy.Abstract
It was established that with the addition of the treatment of hemorrhagic cystitis in cats with the drugs "Urovet phytocomplex" and "Tranexam 250 mg", the normalization of the protein content in the urine and the clinical condition is observed on the 7th day of treatment. The elimination of erythrocyturia and leukocyturia occurs twice as fast as without the use of the specified drugs.
References
Сіренко Р.П., Цвіліховський М.І. Мультицентрове ретроспективне дослідження щодо поширеності ідіопатичного циститу у котів у межах мегаполісу. Науковий вісник ветеринарної медицини. 2021. № 2. С. 123–135.
Франчук-Крива Л.О., Шкільова К.С., Семенченко Н.В. Лікарські рослини з гемостататичною дією. Сучасні світові тенденції розвитку науки та інформаційних технологій : матеріали IІІ міжнар. наук.-практ. конф. (Одеса, 22–23 трав. 2020 р.), Одеса : ГО «Інститут інноваційної освіти», 2020. С. 101–105.
Belayet Hossain M. A case report on haemorrhagic cystitis in a domestic cat. A clinical report submitted in partial satisfaction of the requirements for the Degree of Doctor of Veterinary Medicine. Khulshi, Bangladesh. 2017–2018, 1-17. URL: http://surl.li/esuchf (Date of access: 25.07.2024).
Brossard, C., Lefranc, A. C., Pouliet, A. L., Simon, J. M., Benderitter, M., Milliat, F., & Chapel, A. (2022). Molecular Mechanisms and Key Processes in Interstitial, Hemorrhagic and Radiation Cystitis. Biology, 11 (7), 972. https://doi.org/10.3390/biology11070972
Buffington, C. T., Dennis, J. C., & DiBartola, S. P. (1996). Interstitial cystitis in cats. Veterinary Clinics: Small Animal Practice, 26 (2), 317–326.
deVries, C. R., & Freiha, F. S. (1990). Hemorrhagic cystitis: a review. The Journal of urology, 143(1), 1–9. https://doi.org/10.1016/s0022-5347(17)39848-8
Dorsch R., Remer C., Sauter-Louis C., Hartmann K. (2014). Feline lower urinary tract disease in a German cat population. A retrospective analysis of demographic data, causes and clinical signs. Tierarztl Prax Ausg K Kleintiere Heimtiere, 42 (4):231-239.
Haldar S, Dru C, Bhowmick NA (2014). Mechanisms of hemorrhagic cystitis. Am J Clin Exp Urol., 2 (3): 199–208.
Kaul Elisabeth, Hartmann Katrin, Reese Sven, Dorsch Roswitha (2020). Recurrence rate and long-term course of cats with feline lower urinary tract disease. J Feline Med Surg, 22 (6): 544-556. doi: 10.1177/1098612X19862887
Korkmaz A, Topal T, Oter S. (2007). Pathophysiological aspects of cyclophosphamide and ifosfamide induced hemorrhagic cystitis; implication of reactive oxygen and nitrogen species as well as PARP activation. Cell Biol Toxicol, 23: 303–312.
Kruger, J. M., Osborne, C. A., Goyal, S. M., Wickstrom, S. L., Johnston, G. R., Fletcher, T. F., & Brown, P. A. (1991). Clinical evaluation of cats with lower urinary tract disease. Journal of the American Veterinary Medical Association, 199(2), 211–216.
Leslie, S. W., Hamawy, K., & Saleem, M. O. (2024). Gross and Microscopic Hematuria. In StatPearls. StatPearls Publishing. URL: https://pubmed.ncbi.nlm.nih.gov/30480952/
Lew-Kojrys S., Mikulska-Skupien E., Snarska A., Krystkiewicz W., Pomianowski A. (2017). Evaluation of clinical signs and causes of lower urinary tract disease in Polish cats. Vet. Med. – Czech, 62 (7): 386-393. doi: 10.17221/170/2016-VETMED
Lonc KM, Kaneene JB, Carneiro PAM, Kruger JM. (2020). Retrospective analysis of diagnoses and outcomes of 45 cats with micturition disorders presenting as urinary incontinence. J Vet Intern Med., 34(1): 216-226. doi: 10.1111/jvim.15683
Manikandan R, Kumar S, Lalgudi N. Dorairajan, Hemorrhagic cystitis: A challenge to the urologist. Indian J Urol. 2010; 26 (2): 159–66.
Malani N. Anurag, Kauffman AC. (2007). Candida urinary tract infections: treatment options. Expert Rev Anti Infect Ther., 5 (20) : 277–284. doi: 10.1586/14787210.5.2.277
Paliy A.P., Gujvinska S.O., Alrawashdeh M.S., Shkromada O.I., Dudchenko Yu.A., Kovalenko L.M., Plyuta L.V., Franchuk-Kryva L.O., Kushch L.L., Matsenko O.V. (2020). Selection of technological regime and cryoprotector for lyophilization of lactobacteria (Lactobacillus spp.). Ukrainian Journal of Ecology, 10 (4): 184-190, doi: 10.15421/2020_186
Raab O, Béraud R, Tefft KM, Muckle CA. (2015). Successful treatment of Corynebacterium urealyticum encrusting cystitis with systemic and intravesical antimicrobial therapy. Can. Vet. J., 56 (5): 471-5. PMID: 25969578; PMCID: PMC4399731.
Relling, M. V., & Schunk, J. E. (1986). Drug-induced hemorrhagic cystitis. Clinical pharmacy, 5 (7), 590–597.
Todorov Mykola, Kushnir Volodymyr, Franchuk-Kryva Liubov, & Ulyzko Serhii (2024). Antenatal prophylaxis of acute digestive disorders in calves. BIO Web Conf. ICABEE, 114 (01023): 1-13 doi: https://doi.org/10.1051/bioconf/202411401023
West N. J. (1997). Prevention and treatment of hemorrhagic cystitis. Pharmacotherapy, 17(4), 696–706.
