STRUCTURALLY-FUNCTIONAL CHARACTERISTICS OF PROTEIN PLASMOLEMS OF ENTEROCYTES JEJUNUM OF CATTLE IN THE FETAL PERIOD OF ONTOGENESIS
DOI:
https://doi.org/10.37000/abbsl.2019.94.06Keywords:
fetus, cattle, jejunum, enterocyte polypeptides, apical membrane, basolateral membrane, Fc-γ-receptor proteins, transport enzymes, hydrolytic enzymes.Abstract
In accordance with the stated aim, a theoretical generalization and a new solution to the scientific problem are revealed, which is revealed in new scientific data on the characteristics of the structural components of the mucous membrane of the cavity of cattle fetus, the dynamics of cytometric indices of epithelial cells with a curved border of the cavity of structural proteins of the plasmolema of intestinal epithelial cells and age-related changes in the activity of hydrolytic and transport enzymes on the apical bazolateral membranes and intestinal cells fetus of cattle. For the first time, the polypeptide composition of Fc-γ-receptors of the cell envelope of enterocytes in the fruiting period of ontogenesis was identified, the regularities of formation of modulation of Fc-γ-receptor expression were studied and their localization on plasmolemma of cattle enterocytes was established.
References
2. Fanos V. et al. Selected Lectures of the 13th International Workshop on Neonatology //Journal of Pediatric and Neonatal Individualized Medicine. – 2017. – Т. 6. – №. 2. – С. e060235.
3. Eisenreich W. et al. To eat and to be eaten: mutual metabolic adaptations of immune cells and intracellular bacterial pathogens upon infection //Frontiers in cellular and infection microbiology. – 2017. – Т. 7. – С. 316.
4. Nimmerjahn F, Anthony R., Ravetch J. Agalactosylated IgG antibodies depend on cellular Fc receptors for in vivo activity // Proc Natl Acad Sci U S A. – 2007. – 104, № 20. - 8433-8437.
5. Nimmerjahn F, Ravetch J.V. Fcgamma receptors: old friends and new family members. Immunity. 2006 Jan; 24 (1): 19-28.
6. Usatyuk P.V. Methodical aspects of obtaining isolated small intestinal epithelial cells // Ukr. biochem. . - 1999. - T. 71. - № 2. - P. 10-13.
7. Tsvilikhovsky M.I., Bereza V.I., Nemova T.V., Yakimchuk O.M. Limiting factors and animal pathology of antenatal and postnatal development. Visn. Poltava. state. agrarian. 2014. № 3. S. 92–94.
8. Dickinson B., Badizadegan K., Wu Z. at al. Bidirectional FcRn-dependent IgG transport in a polarized human intestinal epithelial cell line // The Journal of Clinical Investigation. 1999. – 104. P. 903–911.
