SURGICAL STRATEGY FOR EXTENSIVE SKIN WOUND DEFECTS OF THE APPENDICULAR SKELETON IN DOGS AND CATS: A SYSTEMATIC REVIEW

Authors

  • Roman Kazantsev
  • Dmytro Sliusarenko
  • Petro Zaika
  • Kateryna Syniahivska
  • Denys Kryvoruchenko

DOI:

https://doi.org/10.37000/abbsl.2026.118.13

Keywords:

traumatic injuries, sharp objects, skin deficit, scars, limbs, reconstructive surgery, skin stretching, skin flaps, small animals.

Abstract

The study is devoted to a systematic analysis of modern surgical approaches for the management of substantial skin defects of the appendicular skeleton in dogs and cats. The review was conducted based on relevant English-language publications selected from scientometric databases. The paper analyzes the indications, advantages, and limitations of various wound closure methods, including primary, delayed, and secondary closure, as well as healing by secondary intention. Special attention is paid to the issue of tissue stretching and its impact on the course and outcome of wound healing in the distal parts of the limbs. Data on the use of skin tension-relief techniques for small and medium-sized wounds are summarized. The possibilities of using local, distant, and axial skin flaps in the reconstruction of large defects are discussed. Indications for the use of skin grafts are analyzed depending on the condition of the recipient bed and the level of vascularization. The role of muscle and myocutaneous flaps in the treatment of deep wounds with exposure of bones, tendons, or joints is highlighted separately. It is shown that the optimal choice of surgical strategy should be based on the principles of “reconstructive ladders.” Well-vascularized flaps provide higher tissue survival and better clinical outcomes.

Author Biographies

Roman Kazantsev

PhD in Veterinary Medicine, Acting Senior Researcher
National Scientific Center “Institute of Experimental and Clinical Veterinary
Medicine”, Kharkiv, Ukraine
ORCID ID: 0000-0002-4479-1516
E-mail: trilobite@ukr.net

Dmytro Sliusarenko

Doctor of Veterinary Sciences, Professor,
Head of the Department of Veterinary Surgery and Reproductology
State Biotechnological University, Kharkiv, Ukraine
ORCID ID: 0000-0001-8214-0637
E-mail: slusarenkodmitriy@gmail.com

Petro Zaika

Candidate of Veterinary Sciences, Associate Professor,
Associate Professor of the Department of Veterinary Surgery and Reproductology
State Biotechnological University, Kharkiv, Ukraine
ORCID ID: 0000-0003-0321-4795
E-mail: peter.zaika34@gmail.com

Kateryna Syniahivska

Candidate of Veterinary Sciences, Associate Professor,

Associate Professor of the Department of Veterinary Surgery and Reproductology
State Biotechnological University, Kharkiv, Ukraine
ORCID ID: 0000-0003-4482-4813
E-mail: max_milos@ukr.net

Denys Kryvoruchenko

PhD in Veterinary Medicine, Assistant
Assistant Professor of the Department of Veterinary Surgery and Reproductology,
State Biotechnological University, Kharkiv, Ukraine
ORCID ID: 0000-0002-2044-8019
E-mail: denys.kryvoruchenko@gmail.com

References

Albernaz, V. G. P., Oblak, M. L., & Quitzan, J. G. (2021). Angularis oris axial pattern flap as a reliable and versatile option for rostral facial reconstruction in cats. Veterinary Surgery, 50(8), 1688–1695. https://doi.org/10.1111/vsu.13686

Alexopoulos, C., Papadopoulos, E., Charalambous, C., & Karayannopoulou, M. (2022). Locally injected autologous platelet-rich plasma improves cutaneous wound healing in cats. Animals, 12(15), 1993. https://doi.org/10.3390/ani12151993

Amsellem, P. (2011). Complications of reconstructive surgery in companion animals. Veterinary Clinics of North America: Small Animal Practice, 41(5), 995–1006. https://doi.org/10.1016/j.cvsm.2011.05.005

Baines, S. J., Field, E. J., & Demetriou, J. (2017). Short term and long term outcomes of axial pattern skin flaps in dogs and cats: 65 cases. Journal of Small Animal Practice, 58(4), 223–232. https://doi.org/10.1111/jsap.12687

Barnes, K., Lanz, O., Barry, S., & Aulakh, K. (2019). Use of cancellous bone grafting to promote granulation tissue in a distal limb wound in a dog. Journal of Small Animal Practice, 60(7), 450–453. https://doi.org/10.1111/jsap.12855

Bonaventura, N. C., & Ganjei, J. B. (2021). Comparison of outcomes for single-session and delayed full-thickness applications of meshed skin grafts used to close skin defects after excision of tumors on the distal aspects of the limbs in dogs. Journal of the American Veterinary Medical Association, 258(4), 387–394. https://doi.org/10.2460/javma.258.4.387

Bristow, P. C., Halfacree, Z. J., & Baines, S. J. (2015). A retrospective study of the use of active suction wound drains in dogs and cats. Journal of Small Animal Practice, 56(5), 325–330. https://doi.org/10.1111/jsap.12339

Crowley, J. D., Hosgood, G., & Appelgrein, C. (2020). Seed skin grafts for reconstruction of distal limb defects in 15 dogs. Journal of Small Animal Practice, 61(9), 561–567. https://doi.org/10.1111/jsap.13187

de la Puerta, B., Martinez, A., & Buracco, P. (2021). Superficial temporal axial pattern flap for facial reconstruction of skin defects in dogs and cats. Journal of Small Animal Practice, 62(10), 832–839. https://doi.org/10.1111/jsap.13384

Field, E. J., Kelly, G., Pleuvry, D., Demetriou, J., & Baines, S. J. (2015). Indications, outcome and complications with axial pattern skin flaps in dogs and cats: 73 cases. Journal of Small Animal Practice, 56(8), 698–706. https://doi.org/10.1111/jsap.12400

Furneaux, R. W. (2010). Management of distal limb shearing injuries in cats. Journal of Feline Medicine and Surgery, 12(1), 56. https://doi.org/10.1016/j.jfms.2009.12.010

Gaudio, E., Aertsens, A., Field, E., Hattersley, R., & Baines, S. (2023). Short-term outcome and complications following cutaneous reconstruction using cranial superficial epigastric axial pattern flaps in dogs: Six cases (2008–2022). Journal of Small Animal Practice, 64(11), 704–709. https://doi.org/10.1111/jsap.13657

Guzu, M., Rossetti, D., & Hennet, P. R. (2021). Locoregional flap reconstruction following oromaxillofacial oncologic surgery in dogs and cats: Review and decisional algorithm. Frontiers in Veterinary Science, 8, 685036. https://doi.org/10.3389/fvets.2021.685036

Hansen, L. A., Hazenfield, K. M., Olea-Popelka, F., & Smeak, D. D. (2015). Distribution, complications, and outcome of footpad injuries in pet and military working dogs. Journal of the American Animal Hospital Association, 51(4), 222–230. https://doi.org/10.5326/JAAHA-MS-6193

Hunt, G. B. (1995). Skin fold advancement flaps for closing large sternal and inguinal wounds in cats and dogs. Veterinary Surgery, 24(2), 172–175. https://doi.org/10.1111/j.1532-950x.1995.tb01312.x

Hunt, G. B., Tisdall, P. L., Liptak, J. M., Beck, J. A., Swinney, G. R., & Malik, R. (2001). Skin-fold advancement flaps for closing large proximal limb and trunk defects in dogs and cats. Veterinary Surgery, 30(5), 440–448. https://doi.org/10.1053/jvet.2001.25868

Jones, C. A., & Lipscomb, V. J. (2019). Indications, complications, and outcomes associated with subdermal plexus skin flap procedures in dogs and cats: 92 cases (2000–2017). Journal of the American Veterinary Medical Association, 255(8), 933–938. https://doi.org/10.2460/javma.255.8.933

Kodie, D. O., Oyetayo, N. S., Aina, O. O., & Eyarefe, O. D. (2022). Nigeria bee honey enhanced adherence, neovascularisation and epithelisation of full-thickness skin autografts on distal extremities of dogs. BMC Veterinary Research, 18(1), 94. https://doi.org/10.1186/s12917-022-03192-w

Lemarié, R. J., Hosgood, G., Read, R. A., Lewis, D. D., Bellah, R., Salisbury, S. K., & Goldsmid, S. (1995). Distant abdominal and thoracic pedicle skin flaps for treatment of distal limb skin defects. Journal of Small Animal Practice, 36(6), 255–261. https://doi.org/10.1111/j.1748-5827.1995.tb02910.x

Liptak, J. M., & Dernell, W. S. (2017). Axial pattern flap reconstruction following excision of mast cell tumors in dogs: 24 cases. Veterinary Surgery, 46(7), 876–885. https://doi.org/10.1111/vsu.12691

Liptak, J. M., Dernell, W. S., & Withrow, S. J. (2017). Locoregional flap reconstruction following oromaxillofacial tumor excision in dogs and cats. Veterinary Surgery, 46(5), 543–552. https://doi.org/10.1111/vsu.12712

Magidenko, S. R., Peterson, N. W., Pisano, G., & Buote, N. J. (2022). Analysis of patient outcome and owner satisfaction with double limb amputations: 14 dogs and four cats. Journal of the American Veterinary Medical Association, 260(8), 884–891. https://doi.org/10.2460/javma.21.04.0199

Mauer, E. S., Maxwell, E. A., Cocca, C. J., Ganjei, J., & Spector, D. (2021). Acellular fish skin grafts for the management of wounds in dogs and cats: 17 cases (2019–2021). American Journal of Veterinary Research, 83(2), 188–192. https://doi.org/10.2460/ajvr.21.09.0140

Miller, A. J., Cashmore, R. G., Marchevsky, A. M., Havlicek, M., Brown, P. M., & Fearnside, S. M. (2016). Negative pressure wound therapy using a portable single-use device for free skin grafts on the distal extremity in seven dogs. Australian Veterinary Journal, 94(9), 309–316. https://doi.org/10.1111/avj.12474

Moher, D., Liberati, A., Tetzlaff, J., & Altman, D. G. (2010). Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement. International Journal of Surgery, 8(5), 336–341. https://doi.org/10.1016/j.ijsu.2010.02.007

Pavletic, M. M. (2000). Use of an external skin-stretching device for wound closure in dogs and cats. Journal of the American Veterinary Medical Association, 217(3), 350–354. https://doi.org/10.2460/javma.2000.217.350

Pope, E. R. (1990). Mesh skin grafting. Veterinary Clinics of North America: Small Animal Practice, 20(1), 177–187. https://doi.org/10.1016/s0195-5616(90)50009-1

Proot, J. L. J., Jeffery, N., Culp, W. T. N., Buracco, P., de la Puerta, B., Williams, J. M., Ladlow, J. F., Field, E. J., Nelissen, P., Ragni, R. A., Pope, J. F. A., Baines, S. J., Liptak, J. M., & Nicholson, I. (2019). Is the caudal auricular axial pattern flap robust? A multi-centre cohort study of 16 dogs and 12 cats (2005 to 2016). Journal of Small Animal Practice, 60(2), 102–106. https://doi.org/10.1111/jsap.12946

Prpich, C. Y., Santamaria, A. C., Simcock, J. O., Wong, H. K., Nimmo, J. S., & Kuntz, C. A. (2014). Second intention healing after wide local excision of soft tissue sarcomas in the distal aspects of the limbs in dogs: 31 cases (2005–2012). Journal of the American Veterinary Medical Association, 244(2), 187–194. https://doi.org/10.2460/javma.244.2.187

Raske, M., McClaran, J. K., & Mariano, A. (2015). Short-term wound complications and predictive variables for complication after limb amputation in dogs and cats. Journal of Small Animal Practice, 56(4), 247–252. https://doi.org/10.1111/jsap.12330

Riggs, J., Jennings, J. L., Friend, E. J., Halfacree, Z., Nelissen, P., Holmes, M. A., & Demetriou, J. L. (2015). Outcome of full-thickness skin grafts used to close skin defects involving the distal aspects of the limbs in cats and dogs: 52 cases (2005–2012). Journal of the American Veterinary Medical Association, 247(9), 1042–1047. https://doi.org/10.2460/javma.247.9.1042

Sesana, A., Bietzk, E., & Rossanese, M. (2025). Outcome of lip to lid subdermal plexus flaps to reconstruct defects of the lower eyelid in dogs and cats: 46 cases (2005–2022). Journal of Small Animal Practice, 66(12), 918–924. https://doi.org/10.1111/jsap.13914

Shahar, R., Shamir, M. H., Brehm, D. M., & Johnston, D. E. (1999). Free skin grafting for treatment of distal limb skin defects in cats. Journal of Small Animal Practice, 40(8), 378–382. https://doi.org/10.1111/j.1748-5827.1999.tb03104.x

Siefert, T., & Kessler, M. (2020). Outcomes of axial pattern flaps used in distal limb reconstruction in dogs: 28 cases. Veterinary Surgery, 49(4), 643–652. https://doi.org/10.1111/vsu.13398

Siegelmayer, D., & Gradner, G. (2023). Reading man flap in four dogs: A case series. BMC Veterinary Research, 19, 159. https://doi.org/10.1186/s12917-023-03723-z

Siegelmayer, D., Gradner, G., & Martens, A. (2022). Use of subdermal plexus flaps for reconstruction of large facial defects in cats: 9 cases. BMC Veterinary Research, 18, 412. https://doi.org/10.1186/s12917-022-03457-9

Smith, B. J., Ballard, J. B., & Boon, C. (2016). Versatility and outcome of the angularis oris axial pattern flap for facial reconstruction in dogs: 18 cases. Veterinary Surgery, 45(3), 321–329. https://doi.org/10.1111/vsu.12408

Tong, T., & Simpson, D. J. (2012). Free skin grafts for immediate wound coverage following tumour resection from the canine distal limb. Journal of Small Animal Practice, 53(9), 520–525. https://doi.org/10.1111/j.1748-5827.2012.01250.x

Vallefuoco, R., Ritson, K., Taylor, F., Fina, C., & Bello, A. M. (2023). A rotation alar fold flap for cosmetic nasal plane reconstruction: Description of the technique and outcome in three dogs. Veterinary Sciences, 10(11), 647. https://doi.org/10.3390/vetsci10110647

Wallin-Håkansson, N., & Berggren, K. (2017). Orbital reconstruction in the dog, cat, and horse. Veterinary Ophthalmology, 20(4), 316–328. https://doi.org/10.1111/vop.12420

White, R. N., & Boon, C. (2019). Reconstruction of large cutaneous defects using single pedicle rotation flaps in dogs. Veterinary Surgery, 48(1), 142–150. https://doi.org/10.1111/vsu.13141

Published

2026-03-30

How to Cite

Казанцев, Р., Слюсаренко, Д., Заїка, П., Синяговська, К., & Криворученко, Д. (2026). SURGICAL STRATEGY FOR EXTENSIVE SKIN WOUND DEFECTS OF THE APPENDICULAR SKELETON IN DOGS AND CATS: A SYSTEMATIC REVIEW. Agrarian Bulletin of the Black Sea Littoral, (118), 190-211. https://doi.org/10.37000/abbsl.2026.118.13