MODERN APPROACH TO CALCULATING DOSES OF VETERINARY MEDICATIONS

Abstract

The dosage of veterinary drugs is an important and rather responsible part of any therapeutic or preventive measures. That is why the Committee on Medicinal Products for Veterinary Use (CVMP) has created a reflective document on dose revision and adjustment of established veterinary antibiotics. Established veterinary antibiotics are not always used in the approved dose. Doses may need to be reviewed and adjusted to maintain efficacy and limit the selection of resistant mutant target pathogens. However, a dose change can have implications for target animal safety (TAS), withdrawal periods (WP), environmental risk assessment (ERA) and, if applicable, user safety assessment (URA). This means that a lot of research is needed, but marketing permit holders may not have the resources to conduct them. Errors in prescribing medications are a serious problem for patient safety, can be fatal. A significant part of errors in prescribing drugs are caused by incorrect dose calculation. The reason for this is the insufficient level of introduction of modern technologies into the process. Most of the developments are based only on mathematical models and formulas, in which doctors are often confused. It is critically important to identify the elements that contribute to the ability of doctors to perform dosage calculations and to introduce these developments into the course "Veterinary Pharmacology" in higher education institutions. The basis of these developments should be automated calculation codes with a defined algorithm of actions. In this case, the doctor receives the dose calculation only after entering the initial data. This will make the calculation easier and ensure the accuracy of the calculation. A specialist should have an idea not only about calculation formulas, but also about program codes that will provide accurate calculation, about the possibilities of using existing programs for creating spreadsheets. Our developments, which are described in this article, are aimed specifically at helping and improving the accuracy of drug dose counting.