REFERENT ANALYSIS OF “PWL” AND SILK SUTURE MATERIALS IN SKIN-MUSCLE JUNCTIONS
Keywords:
surgery, surgical wounds, wound healing, polyvalerolactone.Abstract
The presented article provides the results of a study dedicated to comparing the effectiveness of two types of suture materials—a polymeric material, PWL (polyvalerolactone, monofilament), developed by NGO “Biopolymer,” Poltava, and traditional silk—for suturing skin-muscle wounds, particularly in operations with access through a median incision of the abdominal wall. During the surgical procedure, special attention was paid to the nature of postoperative wound healing. It was established that tissue regeneration by primary intention occurred significantly more effectively in the group of animals where the PWL thread was used for suturing. Specifically, in 90% of cases in this group, normal healing without complications was observed. In contrast, when a combination of catgut and silk was used, the primary intention healing rate was only 70%. This indicates a higher biological inertness of the polymeric material PWL, which reduces the likelihood of inflammatory complications. The frequency of ligature granuloma detection (a sign of the body's reaction to a foreign material) when using traditional silk was twice as high as when using PWL. In 30% of animals whose wounds were sutured with silk and catgut, serious complications were observed, including purulent suture infections and healing failure, which were not registered in cases using PWL. The study also showed that as early as the second postoperative day, animals whose wounds were sutured with PWL thread had a significant reduction in wound exudation. This led to the disappearance of inflammatory edema and promoted faster tissue defect growth. The less pronounced local reaction to the suture material, in turn, contributed to the overall improvement of the postoperative period.
Thus, the obtained results prove that the choice of suture material is of fundamental importance for the course of the postoperative period and the final result of a surgical intervention. PWL is a promising alternative to traditional suture materials, as it ensures fewer complications, accelerates the healing process, and demonstrates high biocompatibility with the body's tissues.
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