PLATELET HEMOSTASIS OF COWS DURING PREGNANCY
DOI:
https://doi.org/10.37000/abbsl.2022.102.21Keywords:
cow, tilty, haemostasis, thrombocytes, bloodAbstract
Platelet hemostasis of cows during pregnancy acquires significant changes. They indicate that during the period of gestation, the state of vascular-platelet hemostasis of the animal acquires appropriate patterns in the dynamics and activity of individual components as the period of pregnancy increases. The number of platelets in the blood of cows from the first trimester of pregnancy, by the end of the third trimester, decreases respectively by 1.17 (p<0.05), 1.28 (p<0.05) and 1.33 times (p<0.01), and for the entire period of pregnancy by 1.27 times (p<0.01) trimester of pregnancy in cows, prothrombin time was 1.37 times, and at the end of the third trimester of pregnancy, prothrombin time of hemostasis in cows decreased by 1.52 times (p<0.001) compared with this indicator of cows in the control group. In pregnant cows, the prothrombin time of hemostasis decreased from the first trimester of pregnancy to the end of the third by 1.27 times (p<0.01) and averaged 32.11±2.19 sec. In infertile cows during the entire period of research, the present time ranged from 43.20 ± 0.16 sec to 43.52 ± 0.70 sec, that is, it practically did not change. On average, for the entire period of pregnancy in cows, the prothrombin time was 1.34 times less than in noncalving cows (p<0.01). We found similar dynamics of changes in the prothrombin hemostasis index of cows. In cows from the first trimester to the end of the third trimester of pregnancy, the prothrombin index consistently decreased by 1.14 times (p<0.05). The international normalized ratio during pregnancy in cows decreased by 1.16 times (p<0.05). We found significant changes in the content of fibrinogen in the blood of cows. In calf animals, the content of fibrinogen in the blood gradually increased and at the end of the third trimester of pregnancy it was 1.31 times higher (p<0.01). On average, over the entire period of research, the content of fibrinogen in the blood of calving cows was 1.12 times higher (p<0.05) than in calf animals. Changes in the dynamics of indicators of prothrombin and thrombin time of hemostasis, fibrinogen content in the blood of cows for the entire period of pregnancy affect the properties of the blood. By the end of the second and third trimesters, the blood viscosity of cows increased by 1.15 (p < 0.05) - 1.34 times (p <0.01). The rate of blood clotting in pregnant cows during the period of gestation also increased.
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